NVL-655
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2739866-40-9
ALK-IN-27
ALK
Protein Tyrosine Kinase
C23H22ClFN6O
NVL-655 is a selective inhibitor of anaplastic lymphoma kinase (ALK), with potential antineoplastic activity in the Ba/F3 xenograft model. It also exhibits significant inhibitory activity against ROS1, LTK, PYK2, TRKB, and FAK, with an IC50 ≤10-fold ALK and demonstrates high potency against specific ALK mutations, with an IC50 of <0.73 nM, 7 nM, 3 nM, 3 nM for G1202R, G1202R/L1196M, G1202R/G1269A and G1202R/L1198F respectively.
Beschrijving
NVL-655 Beschikbaar in 100 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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