O-Arachidonoylglycidol-d5
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
O-Arachidonoyl glycidol-d5 is the deuterium labeled O-Arachidonoyl glycidol. O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 μM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 μM, respectively[1].
2519458-54-7
12352005
Cannabinoid Receptor; Isotope-Labeled Compounds
GPCR/G Protein; Neuronal Signaling; Others
Metabolic Disease
O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)OC([2H])(C1(OC1([2H])[2H])[2H])[2H]
C23H31D5O3
365.56
[1]Cisneros JA, et al. Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. J Med Chem. 2007 Oct 4;50 (20) :5012-23.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W742940/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
O-Arachidonoyl glycidol-d5 is the deuterium labeled O-Arachidonoyl glycidol. O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-A
Specificaties
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