O-fenantholine
Gecertificeerd

O-fenantholine

Catalog #: C12249-01
Maat: 25 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

66-71-7

Synonyms

1,10-Phenanthroline, phen

SKU

C12249-25mg

Target

MMP

Applications

Proteases

Smiles

C1=CC2=C (C3=C (C=CC=N3) C=C2) N=C1

Molecular Formula

C12H8N2

Additionnal Information

O-Phenanthroline (1,10-Phenanthroline, phen), a hypoxia-mimicking agent, is a non-specific matrix metalloproteinase (MMP) inhibitor with IC50 of 110.5μM for Collagenase. O-phenanthroline reduces the expression of MMP3 and MMP13 mRNA levels during chondrogenic differentiation of human chondrocytes (hChs), as well as after TNFα/IL-1β exposure in an explant model. o-Phenanthroline is also a metal chelator which prevents the induction of chromosomal aberrations in streptozotocin-treated cells and forms a red chelate with Fe2+ that absorbs maximally at 510 nm.

Storage Conditions

3 years -20°C powder

Beschrijving

O-fenantholine Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamO-fenantholine
Categorie
Beschikbare grootte25 mg
CatalogusnummerC12249-01