O-Glycoprotease
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6xHis tag at the C-terminus. The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn2+.
12352204
Endonuclease
Cell Cycle/DNA Damage
Inflammation/Immunology
[O-Glycoprotease]
[1]Riley NM, et al. Deciphering O-glycoprotease substrate preferences with O-Pair Search. Mol Omics. 2022 Dec 5;18 (10) :908-922.
Blue Ice
Store at -20°C for 2 years
http://file.medchemexpress.com/batch_PDF/HY-E70565/O-Glycoprotease-SDS-MedChemExpress.pdf
Enzyme
No Development Reported
Beschrijving
O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-typ
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