OAT Antilichaam - middengebied: Biotine (ARP48134_P050-Biotine)

Ornithine aminotransferase

OKT, GACR, HOGA, OATASE

4942

P04181

NP_000265

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human OAT

OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB459793.1 27-68 43-2062 BC016928.1 1-2020 2063-2066 M12267.1 2010-2013

FUS; HUWE1; SUMO2; STAU1; UBC; ADRB2; ATF2; CTSA; FBXO6; UBQLN4; CDK2; SIRT7; NUDT3; HDAC5; MYC; ICT1; OTUD4; DMWD; SLC35F6; OAT; EIF6

Biotin

Polyclonal Antibody

WB

Affinity Purified

OAT is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Wet Ice

439

OAT

OAT

Rabbit

Ornithine aminotransferase, mitochondrial

NM_000274

RTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMV