OCIAD1 Antilichaam

OCIAD1 Antibody: OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid- (LPA-) induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.

54940

Q9NX40

NP_060300

Human

Unconjugated

Primary Antibodies

Cancer

OCIAD1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1210 - HEK293 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (100%), Rat: (94%)

OCIAD1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

OCIAD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

OCIAD1

Cat. No. 17-010 - HEK293 Cell Slide

OCIA domain containing 1

Homo sapiens

Luo LY, Soosaipillai A, and Diamandis EP. Molecular cloning of a novel human gene on chromosome 4p11 by immunoscreening of an ovarian carcinoma cDNA library. Biochem. Biophys. Res. Commun.2001; 280:401-6.

Sengupta S, Michener CM, Escobar P, et al. Ovarian cancer immuno-reactive antigen domain containing 1 (OCIAD1), a key player in ovarian cancer cell adhesion. Gynecologic Oncol.2008; 109:226-33.

OCIAD1 Antibody: OCIA, ASRIJ, TPA018, OCIA, OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen

ELISA, WB, IF

8923427

Liquid