Oct-1 Antilichaam

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

5451

P14859

NP_001185712.1

Human, Mouse, Rat

Oct-1 antibody was raised against a peptide sequence around aa.270~274 (T-P-K-R-I) derived from Human Oct-1.

Unconjugated

Primary Antibodies

Stem Cell

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

90 kDa

This antibody detects endogenous level of total Oct-1protein.

Western Blot: 1:500~1:1000

POU2F1

POU class 2 homeobox 1

Homo sapiens

Prefontaine G. G., Walther R., Giffin W., Lemieux M. E., Pope L., Hache R. J. G. J. Biol. Chem, 274:26713-26719 (1999) Mahajan S. S., Wilson A. C. Mol. Cell. Biol. 20:919-928 (2000)

OCT1, OTF1, oct-1B, 41183

WB

311771667

Liquid