OCT-4 Antilichaam

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') . Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

5460

Q01860

NP_002692.2

Human

OCT-4 antibody was raised against a peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4.

Unconjugated

Primary Antibodies

Stem Cell

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

45 kDa

This antibody detects endogenous level of total OCT-4 protein.

Western Blot: 1:1000

POU5F1

POU class 5 homeobox 1

This antibody was raised against a peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4

Pesce, M. and Scholer, H. R. (2001) Stem Cells 19, 271-278. Pan, G. and Thomson, J. A. (2007) Cell Res 17, 42-9. Cauffman, G. et al. (2006) Stem Cells 24, 2685-91.

OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, CDKN6, Otc3

WB

42560248

Liquid