Octreotide-13C9,15N

Octreotide-13C9,15N (SMS 201-995-13C9,15N) is 13C and 15N labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly[1][2].

SMS 201-995-13C9,15N

12352211

Isotope-Labeled Compounds

Others

Metabolism-protein/nucleotide metabolism

Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

O=[13C](N[C@@H]1CC2=CNC3=CC=CC=C23)[13C@H]([13CH2][13C]4=[13CH][13CH]=[13CH][13CH]=[13CH]4)[15NH]C([C@@H](NC([C@@H](CC5=CC=CC=C5)N)=O)CSSC[C@@H](C(N[C@@H]([C@@H](C)O)CO)=O)NC([C@]([H])([C@@H](C)O)NC([C@H](CCCCN)NC1=O)=O)=O)=O

C40 13C9H66N9 15NO10S2

1029.17

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P0036S3/

Isotope-Labeled Compounds

No Development Reported