OGDH Antilichaam

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO (2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

4967

Q02218

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human OGDH (NP_001003941.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 116kDa

IgG

OGDH

Mouse heart

Mouse brain

Oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

Homo sapiens

OGDH, AKGDH, E1k, OGDC

WB, IHC, IF

Liquid