OGFOD1 Antilichaam

OGFOD1 Antibody: OGFOD1, a member of the 2-OG-Fe (II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.

55239

Q8N543

NP_060703

Human, Mouse

Unconjugated

Primary Antibodies

Apoptosis

OGFOD1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

OGFOD1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

OGFOD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist; this antibody will only detect the larger isform.

OGFOD1

2-oxoglutarate and iron-dependent oxygenase domain containing 1

Homo sapiens

Saito K, Adachi N, Koyama H et al. OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. FEBS Lett. 2010; 584:3340-7.

Wehner KA, Schutz S and Sarnow P. OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress. Mol. Cell. Biol. 2010; 30:2006-16.

Marina O, Hainz U, Biernacki MA, et al. Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens. Cancer Res. 2010; 70:1344-55.

OGFOD1 Antibody: TPA1, KIAA1612, TPA1, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, Termination and polyadenylation 1 homolog

ELISA, WB, IF

94536836

Liquid