OLEG1 Antilichaam

The oligodendrocyte transcription factors 1 and 2 (OLIG1 and OLIG2, respectively) make up part of basic helix-loop-helix (bHLH) family of transcription factors that are specifically expressed in zones of the neuroepithelium from which oligodendrocyte precursors emerge (1) . Both OLIG1 and OLIG2 genes are downstream targets of Sonic hedgehog and are expressed exclusively in the central nervous system (2) . OLIG1 is first expressed in the dorsal portion of the p3 progenitor domain of the ventral neural tube while OLIG2 is first observed in the ventral most p3 domain (2) . OLIG1 has been shown to be a SMAD cofactor involved in cell motility induced by transforming growth factor-beta (TGF-beta) (3) .

116448

Q8TAK6

NP_620450

Human

Unconjugated

Primary Antibodies

Stem Cell

OLIG1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1203 - A549 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rat: (83%), Mouse: (78%)

OLIG1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

OLIG1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

OLIG1 antibody is human specific. It is predicted to not cross-react with other members of the OLIG family of proteins.

OLIG1

Cat. No. 10-301 - Human Brain Tissue Slide

Oligodendrocyte transcription factor 1

Homo sapiens

Zhou Q, Wang S, and Anderson DJ. Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron 2000; 25:331-43.

Lu QR, Yuk D, Alberta JA, et al. Sonic Hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron 2000; 25:317-29.

Motizuki M, Isogaya K, Miyake K, et al. Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-b. J. Biol. Chem. 2013; 288:18911-22.

OLIG1 Antibody: BHLHB6, BHLHE21, BHLHB6, Oligodendrocyte transcription factor 1, Class B basic helix-loop-helix protein 6, Oligo1

ELISA, WB, IHC-P, IF

237757328

Liquid