Olivetol-d9

Olivetol-d9 is the deuterium labeled Olivetol. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activities.

137125-92-9

12352005

Cannabinoid Receptor; Cytochrome P450; Isotope-Labeled Compounds

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Neuroscience-Neuromodulation

Neurological Disease

10 mM in DMSO

OC1=CC(CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=CC(O)=C1

C11H7D9O2

189.30

[1]Jiang R, et al. Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19. Drug Metab Pharmacokinet. 2013;28 (4) :332-8.; Yamaori S, et al. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Drug Metab|[2]Yamaori S, et al. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Drug Metab Dispos. 2011 Nov;39 (11) :2049-56.|[3]Yamaori S, et al. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Drug Metab Dispos. 2011 Nov;39 (11) :2049-56.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W008364S1/

Isotope-Labeled Compounds

No Development Reported