![Onbekende specificiteit (isotype controle) Recombinant antilichaam [MOPC-21] (OAAV00177)](/_ipx/q_80/productPlaceholder.webp)
Onbekende specificiteit (isotype controle) Recombinant antilichaam [MOPC-21] (OAAV00177)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Notch receptor 2
AGS2; HJCYS; hN2; neurogenic locus notch homolog protein 2; notch 2; Notch homolog 2.
4853
P01730
NP_001186930.1
NRR of mouse Notch 2.
This chimeric rabbit antibody was made using the variable domain sequences of the original human scFv format, for improved compatibility with existing reagents, assays and techniques.
• Recombinant Monoclonal
B9
Monoclonal Antibody
Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity) . Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation (PubMed:29149593) . Positively regulates self-renewal of liver cancer cells (PubMed:25985737) .
PBS with 0.02% Proclin 300.
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
IgG, kappa
An engineered ScFv fragment antibody that binds to both mouse mNRR2 and human hNRR2 but not NRR1.
NOTCH2
Rabbit
Neurogenic locus notch homolog protein 2
NOTCH2
NM_001200001.1
Beschrijving
Onbekende specificiteit (isotype controle) Recombinant antilichaam [MOPC-21] (OAAV00177) Beschikbaar in 200 µg. Bestel eenvoudig online met snelle levering.
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