Onc112

1273548-87-0

Antibacterial

Microbiology/Virology

Onc112 is a proline-rich antimicrobial peptide that exhibits potent activity against Gram-negative bacteria. It functions by inhibiting translation through blocking and destabilizing the initiation complex.

C(=O)([C@H]1N(C([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC(=O)[C@H]4N(C(=O)[C@H]5N(C([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CC(O)=O)=O)CCCCN)=O)CCC5)CCC4)CC6=CC=C(O)C=C6)=O)CC(C)C)=O)CCC3)CCCNC(=N)N)=O)CCC2)CCCNC(=N)N)=O)CCC1)N7[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](CC8=CC=C(O)C=C8)C(N[C@H](C(N[C@H](CCCNC(=N)N)C(N)=O)=O)CC(N)=O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC7

C109H177N37O24

2389.8

Ice Packs

-20°C