Oncstatine M Recombinant eiwit

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant human Oncostatin M is a 26.0 kDa protein, containing 227 amino acid residues.

5008

P13725

NP_065391.1

Recombinant Proteins

E. coli

Chemokines & Cytokines, Immunology, Signal Transduction

Room Temp

The lyophilized Oncostatin M recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Oncostatin M is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Oncostatin M recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Oncostatin M

Homo sapiens

Oncostatin-M, OSM

Human

10092621

Lyophilized