Onderzoeksgrade Glofitamab

GlofitamabisaT-cell-engagingbispecificantibodypossessinganovel2:1structurewithbivalencyforCD20onBcellsandmonovalencyforCD3onTcells.Glofitamabisaninvestigational, T-cellbispecificantibodywithadistinctivedesignthatfeatures2FabarmsforbindingCD20onBcells, alongwith1FabarmforbindingCD3onTcells.TheCD3bindingarmisfuseddirectlytooneoftheCD20-bindingarmsinahead-to-tailfashionviaashortflexiblelinker.

Bispecific, CD20-TCB (2:1), RG-6026, CAS:2229047-91-8

Mammalian Cells

B-lymphocytesurfaceantigenB1, Membrane-spanning4-domainssubfamilyAmember1, MS4A1, LeukocytesurfaceantigenLeu-16, B-lymphocyteantigenCD20, Bp35, CD20, T3E, T-cellsurfaceantigenT3/Leu-4epsilonchain, CD3e, CD3E, T-cellsurfaceglycoproteinCD3epsilonchain

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Protein A/G purified from cell culture supernatant.

1.06mg/ml

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Liquid

0.01M PBS, pH7.4.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at4°C short term (1-2weeks) . Store at-20°C 12 months. Store at -176°C long term.

For research use only. Not suitable for clinical or therapeutic use.

0.01M PBS, pH7.4.

Human

IgG1-kappa-lambda