OPRK1 Antilichaam

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

4986

P41145

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRK1 (NP_000903.2) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 40kDa

IgG

OPRK1

Rat brain

Opioid receptor, kappa 1

Homo sapiens

OPRK1, KOR, OPRK, KOR-1, K-OR-1

WB, IHC, IF

Liquid