Optineurine (OPTN) Mouse Monoclonal Antibody [Kloon ID: LBI7H2]

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) OPTN mouse monoclonal antibody, clone LBI7H2

ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP

Homo sapiens optineurin (OPTN), transcript variant 1, mRNA.

10133

Q96CV9

Unconjugated

WB 1:2000, IHC 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

OPTN

https://www.ncbi.nlm.nih.gov/gene/?term=10133

https://www.uniprot.org/uniprot/Q96CV9