Ordastobart
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Ordastobart (INBRX-106; ES-102) is a hexavalent OX40 agonist antibody. Ordastobart enhances OX40 receptor clustering, signaling, and downstream activation, thereby increasing the proliferation and activation of CD4+ and CD8+ T cells in vitro and in vivo. Ordastobart exhibits anti-tumor effects and improves survival in mouse models of cancer. Ordastobart is indicated for research in cancers such as fibrosarcoma and colorectal cancer[1].
2708115-83-5
INBRX-106; ES-102
12352203
Orexin Receptor (OX Receptor)
GPCR/G Protein; Neuronal Signaling
Cancer-programmed cell death
Cancer; Inflammation/Immunology
98
[Ordastobart]
[1]Rowell E, et al. 856 INBRX-106: a novel hexavalent anti-OX40 agonist for the treatment of solid tumors[J]. Journal for ImmunoTherapy of Cancer, 2021, 9 (Suppl 2) : A897-A897.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991336/Ordastobart-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
Ordastobart (INBRX-106; ES-102) is a hexavalent OX40 agonist antibody. Ordastobart enhances OX40 receptor clustering, signaling, and downstream activation, ther
Specificaties
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