Oscillamide C (TFA)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Oscillamide C TFA (Compound 2), a ureido-containing cyclic peptide, is a Protein phosphatase 1 (PP1) and Protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.90 and 1.33 μM for PP1 and PP2A, respectively. Oscillamide C TFA can be isolated from the cyanobacteria Planktothrix agardhii and P. rubescens. Oscillamide C TFA can be used for cancers research[1].
12352209
Phosphatase
Metabolic Enzyme/Protease
Cancer-programmed cell death
Cancer
O=C(O)C(F)(F)F.OC(C=C1)=CC=C1CC[C@@H]2N(C([C@@H](NC([C@](NC([C@@H](CCCCNC([C@@H](NC2=O)CC3=CC=CC=C3)=O)NC(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)([H])[C@@H](C)CC)=O)CCC4=CC=C(C=C4)O)=O)C
C51H69F3N10O12
1071.15
[1]Sano T, et al. Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp. J Nat Prod. 2001 Aug;64 (8) :1052-5.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P11336A/
Peptides
No Development Reported
Beschrijving
Oscillamide C TFA (Compound 2), a ureido-containing cyclic peptide, is a Protein phosphatase 1 (PP1) and Protein phosphatase 2A (PP2A) inhibitor with IC50s of 0
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