Oscillamide Y

Oscillamide Y (Compound 1), a ureido-containing cyclic peptide, is a Chymotrypsin inhibitor. Oscillamide Y can be isolated from freshwater toxic cyanobacterium Oscillatoria agardhii. Oscillamide Y has potent toxicity against fish, daphnid magna and algae with a stimulatory effect for Raphidocelis subcapitata (EC50: 4.62 mg/L) . Oscillamide Y induces high luminescence inhibition in Aliivibrio fischeri. Oscillamide Y can be used for ecological development research[1][2].

168482-80-2

12352209

Bacterial; Ser/Thr Protease

Anti-infection; Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Others

OC(C=C1)=CC=C1CC[C@@H]2NC([C@](NC([C@@H](CCCCNC([C@@H](NC([C@@H](N(C2=O)C)C)=O)CC3=CC=CC=C3)=O)NC(N[C@H](C(O)=O)CC4=CC=C(C=C4)O)=O)=O)([H])[C@H](C)CC)=O

C45H59N7O10

857.99

[1]Zorrilla JG, et al. Ecotoxicological assessment of cyclic peptides produced by a Planktothrix rubescens bloom: Impact on aquatic model organisms. Environ Res. 2024 Sep 15;257:119394. |[2]Sano T, et al. Oscillamide Y, a chymotrypsin inhibitor from toxic Oscillatoria agardhii[J]. Tetrahedron Letters, 1995, 36 (33) : 5933-5936.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11335/

Peptides

No Development Reported