OSMR Antibody - N-terminal regio : FITC (ARP46395_P050-FITC)

Oncostatin M receptor

OSMRB, PLCA1, IL-31RB, OSMRbeta, IL-31R-beta

9180

Q99650

NP_003990

Human, Cow, Dog

The immunogen is a synthetic peptide directed towards the N terminal region of human OSMR

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; CUL5; GAPDH; IL6ST; OSM; JAK2; JAK1; ERBB2

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

OSMR is supported by BioGPS gene expression data to be expressed in HT1080

0.5 mg/ml

Cow: 77%; Dog: 79%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

110kDa

Arita, K., (2008) Am. J. Hum. Genet. 82 (1), 73-80

Wet Ice

979

OSMR

OSMR

Rabbit

Oncostatin-M-specific receptor subunit beta

NM_003999

YQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYHQELKMVFQIQ

Beta