Ossamycine

Ossamycin is a macrolide antibiotic. Ossamycin has anti-fungal effect, and it has weaker anti-Gram-positive bacterial effect. Ossamycin inhibits L cells, Epstein-Barr ascites cancer cells, KB cells, sarcoma-180 cells, L-1210 cells, HeLa cells in cell culture with IC50s (μg/mL) of 0.007, 0.008, 0.005, 0.008, 0.003, 0.005, respectively[1].

2057463-74-6

12352005

Bacterial; Fungal

Anti-infection

Infection

CC[C@@H](O)C[C@@H]1O[C@]2(CCC1)O[C@@]3([H])C[C@]4([C@@](/C=C/CCCCC[C@@](O)([C@@H]([C@H]([C@@H]([C@H]([C@@H]([C@](O)(/C=C/C(O[C@@]([C@@H]3C)([H])C2)=O)C)O)C)O)O[C@@H]5O[C@H]([C@H](CC5)N(C)C)C)O)C)([H])CC(C)(O4)C)O

C49H85NO14

912.20

[1]Oksana Bilyk, et al. The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety. PLoS One. 2019 Apr 30;14 (4) :e0215958.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14853/

Natural Products

No Development Reported