Osteogagerine Antilichaam

Osteoprotegerin (OPG) is a member of the TNF receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of the gene have been reported, but their full length nature has not been determined.

4982

O00300

O00300

Human

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hOPG (human Osteoprotegrin) .

Unconjugated

Primary Antibodies, Antibody Pairs

Signal Transduction

Anti-hOPG specific antibody was purified by affinity chromatography employing immobilized hOPG matrix.

Batch dependent

None

Room Temp

Osteoprotegerin antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

TNFRSF11B

Tumor necrosis factor receptor superfamily, member 11b

Homo sapiens

OPG, TR1, OCIF, OPG, Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor

ELISA, WB

322510101

Lyophilized