OXS007417
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
OXS007417 induces differentiation of acute myeloid leukemia cells (EC50 = 48 nM) in vitro and shows antitumor effects in vivo.
2761147-94-6
12352005
Microtubule/Tubulin
Reference compound
Cell Cycle/DNA Damage; Cytoskeleton
Cancer-programmed cell death
Cancer
https://www.medchemexpress.com/oxs007417.html
10 mM in DMSO
FC(F)OC(C=C1)=CC=C1N2C=NC3=CN=C(C4=C(C)C=C(F)C=C4)C=C32
C20H14F3N3O
369.34
[1]Josa-Culleré L, et al. A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo. J Med Chem. 2021 Nov 11;64 (21) :15608-15628.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-139877/
Reference compound1
No Development Reported
Beschrijving
OXS007417 induces differentiation of acute myeloid leukemia cells (EC50 = 48 nM) in vitro and shows antitumor effects in vivo.
Specificaties
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