Oxyfenbutazon (standaard)

Oxyphenbutazone (Standard) is the analytical standard of Oxyphenbutazone. This product is intended for research and analytical applications. Oxyphenbutazone is a Phenylbutazone metabolite, with anti-inflammatory effect. Oxyphenbutazone is an orally active non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2].

129-20-4

12352100

Bacterial; COX; Reference Standards

Anti-infection; Immunology/Inflammation; Others

Infection; Inflammation/Immunology

O=C(C1CCCC)N(C2=CC=CC=C2)N(C3=CC=C(O)C=C3)C1=O

C19H20N2O3

324.37

[1]Saleem S, et al. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β-catenin signaling pathway. Mol Cell Biochem. 2018 Jul;444 (1-2) :187-196.|[2]Gold B, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A. 2012 Oct 2;109 (40) :16004-11.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1355AR/

Reference Standards