Oxytetracycline-13C, d3 (hydrochloride)

Oxytetracycline-13C, d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride. Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity[1][2][3][4].

12352005

Antibiotic; Bacterial; HSV; Isotope-Labeled Compounds

Anti-infection; Others

Infection

O=C(C(C1=O)=C(O)[C@@H](N([13C]([2H])([2H])[2H])C)[C@]2([H])[C@@H](O)[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N.Cl

C21 13CH22D3ClN2O9

500.91

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Elia AC, et al. Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem. 2014 Aug;40 (4) :1055-68.|[3]Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285 (36) :27509-15.|[4]Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8 (1) : 6-8.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W755036/

Isotope-Labeled Compounds

No Development Reported