Oxytetracycline (calcium)

Oxytetracycline calcium is an antibiotic belonging to the tetracycline class. Oxytetracycline calcium potently inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline calcium is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline calcium also possesses anti-HSV-1 activity[1][2][3].

7179-50-2

12352005

Antibiotic; Bacterial; Endogenous Metabolite; HSV

Anti-infection; Metabolic Enzyme/Protease

COVID-19-anti-virus

Infection

10 mM in DMSO

O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])[C@@H](O)[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N.[Ca]

C22H24CaN2O9

500.51

[1]Elia, A.C., et al., Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem, 2014.|[2]Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285 (36) :27509-15.|[3]Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8 (1) : 6-8.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B0275C/

Reference compound1

Launched

HSV-1; Human Endogenous Metabolite; Microbial Metabolite; Tetracycline