Oxytetracycline-d6

Oxytetracycline-d6 is deuterium labeled Oxytetracycline. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity[1][2][3][4].

12352005

Antibiotic; Bacterial; Endogenous Metabolite; HSV; Isotope-Labeled Compounds

Anti-infection; Metabolic Enzyme/Protease; Others

COVID-19-anti-virus

Infection

NC(C1=C(O)[C@@H](N(C([2H])([2H])[2H])C([2H])([2H])[2H])C2[C@@H](O)C(C3=C(O)[C@]2(O)C1=O)[C@](C)(O)C4=CC=CC(O)=C4C3=O)=O

C22H18D6N2O9

466.47

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8 (1) : 6-8.|[3]Elia, A.C., et al., Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem, 2014.|[4]Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285 (36) :27509-15.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B0275S/

Isotope-Labeled Compounds

No Development Reported