P131
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
P131 is a PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain. P131 can degrade both wild-type and C481S mutant BTK with nanomolar potencies.
2360561-66-4
12352005
PROTAC Linkers
PROTAC
Cancer
NC1=NC=NC2=C1C(C3=CC=C(C=C3)OC4=CC=CC=C4)=NN2[C@@H]5CCCN(C5)C(C6=CN(N=N6)CCOCCOCCOCCNC7=C8C(N(C(C8=CC=C7)=O)C9CCC(NC9=O)=O)=O)=O
C46H48N12O9
912.95
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W591307/
Reference compound1
No Development Reported
Beschrijving
P131 is a PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain. P131 can degrade both wild-type and C481S mutant B
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