P18 INK4c (CDKN2C) Mouse Monoclonal Antibody [Kloon ID: LBI6B3]

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) CDKN2C mouse monoclonal antibody, clone LBI6B3

INK4C; p18; p18-INK4C

Homo sapiens cyclin dependent kinase inhibitor 2C (CDKN2C), transcript variant 1, mRNA.

1031

P42773

Unconjugated

Cell cycle

Cell cycle

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CDKN2C

https://www.ncbi.nlm.nih.gov/gene/?term=1031

https://www.uniprot.org/uniprot/P42773