P53-hDM2-cyclische peptideremmer 16e
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
P53-hDM2 cyclic peptide inhibitor 16e is a p53-hDM2 cell-permeable peptide inhibitor with an IC50 of 9.24 nM for hDM2. p53-hDM2 cyclic peptide inhibitor 16e can be used for cancers like breast, colorectal and cervical cancers research[1].
12352209
MDM-2/p53
Apoptosis
Cancer-programmed cell death
Cancer
O=C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H]2CC3=CC=C(O)C=C3)=O)CCC(O)=O)=O)CSCCCCCCSC[C@H](NC([C@@H](NC2=O)CC4=CNC5=C4C=CC=C5)=O)CNC(N[C@H](CNC(N[C@H](CNC(N)=O)C(C)C)=O)C)=O)=O)=O)[C@H](O)C)[C@H](CCCCN)NC(C)=O
C69H102N16O15S2
1459.78
[1]Neuville M, et al. Cell-Permeable Peptide Inhibitors of the p53-hDM2 Interaction via Foldamer Helix Mimicry and Bis-Thioether Stapling. J Med Chem. 2025 Jan 9;68 (1) :236-246.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P11036/
Peptides
No Development Reported
Beschrijving
P53-hDM2 cyclic peptide inhibitor 16e is a p53-hDM2 cell-permeable peptide inhibitor with an IC50 of 9.24 nM for hDM2. p53-hDM2 cyclic peptide inhibitor 16e can
Specificaties
Recent bekeken producten
Optical EtBr filter, 610 nm for SmartView Pro Imager System, 1100 & 2100 series (for UV)
UVCI-1100-EB
1 Unit
AGPAT4 Antibody
MBS7124622-01
0.05 mL
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Salicylate hydroxylase, Microorganism
HY-E70520-01
1 KU
Purified Diphtheria Toxoid protein (cGMP/USP, vaccine grade, ~1500-2500 Lf/ml; Low endotoxin)
DTOX16-N-500
500 µg
BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
Recent gezochte producten
M-90-422 AF Systems Consumables
131576
Box of 180 Label(s)
Consumable Pack M996030
WAT1096
1 Each
Consumable Pack M996039
WAT1108
1 Each
Consumable Pack M996034
WAT1106
1 Each
Consumable Pack M996038
WAT1102
1 Each
Consumable Pack M996037
WAT1098
1 Each
Consumable Pack M996043
WAT1088
1 Each
Gene gun consumables
E1653
1 Unit