P56Dok 2 (Ab 299) Antilichaam

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

9046

O60496

NP_003965.2

Human

P56Dok-2 (Ab-299) antibody was raised against a peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human p56Dok-2.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

56 kDa

This antibody detects endogenous level of total p56Dok-2 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

DOK2

Docking protein 2, 56kDa

Homo sapiens

Feng Cong, et, al. (1999) Mol. Cell. Biol; 19: 8314 - 8325. Serge Lemay, et, al. (2000) Mol. Cell. Biol; 20: 2743 - 2754. Ute Schaeper, et, al. (2000) J. Cell Biol; 149: 1419. Miyuki Honma, et, al. (2006) Genes Cells; 11: 143 - 151.

P56DOK, p56dok-2, CHK1, DOK2

WB, IHC, IF

41406050

Liquid