P95 NBS1 (NBN) Mouse Monoclonal Antibody [Kloon ID: UMLBI99]

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) NBN mouse monoclonal antibody, clone UMLBI99

AT-V1; AT-V2; ATV; NBS; NBS1; P95

Homo sapiens nibrin (NBN), transcript variant 1, mRNA.

4683

O60934

Unconjugated

Homologous recombination

Homologous recombination

IHC 1:100, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

NBN

https://www.ncbi.nlm.nih.gov/gene/?term=4683

https://www.uniprot.org/uniprot/O60934