PAC-1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 μM.1 It is less potent at activating procaspase-7, EC50=4.5 μM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3
Unconjugated
Off-white solid
-20°C
Beschrijving
PAC-1 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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