Paclitaxel-maleimide

Paclitaxel-maleimide is Paclitaxel modified with a maleimide linker. Paclitaxel-maleimide shows strong BSA binding ability. Paclitaxel-maleimide can be used in tumor research[1].

254893-84-0

12352005

Drug Derivative

Others

Cancer

CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCN5C(C=CC5=O)=O)=O)[C@H](C6=CC=CC=C6)NC(C7=CC=CC=C7)=O)=O)C)C)O)OC(C8=CC=CC=C8)=O)=O

C54H56N2O17

1005.03

[1]Lou X, et al. Pure redox-sensitive paclitaxel-maleimide prodrug nanoparticles: Endogenous albumin-induced size switching and improved antitumor efficiency. Acta Pharm Sin B. 2021 Jul;11 (7) :2048-2058.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-186000/

Reference compound

No Development Reported