PACRG Antilichaam

This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

135138

Q96M98

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human PACRG (NP_001073847.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 35kDa

IgG

WB: 1:500 - 1:2000

PACRG

A-549

BxPC-3

Raji

Mouse testis

Mouse lung

PARK2 co-regulated

Homo sapiens

PACRG, GLUP, HAK005771, PARK2 co-regulated, PARK2CRG, RP3-495O10.2, PARK2 coregulated gene protein

WB

Liquid