PADI2 Antilichaam

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

11240

Q9Y2J8

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 26-210 of human PADI2 (NP_031391.2) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

Mouse spleen

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa

IgG

WB: 1:500 - 1:2000

PADI2

Rat brain

Peptidyl arginine deiminase, type II

Homo sapiens

PADI2, KIAA0994, PAD-H19, PAD2, PDI2

WB

Liquid