PADRE-peptide

PADRE peptide is a universal peptidic epitope. PADRE peptide binds to pan HLA-DR receptors, present on specific T cells. PADRE peptide can be inserted into trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) or hamster polyomavirus (HaPyV) -derived VP1 for construction of chimeric virus-like particles (VLPs), therefore activating dendritic cells and T cells and inducing strong immune responses and. PADRE peptide can be used for the development of vaccines[1].

161147-59-7

12352209

MHC

Immunology/Inflammation

Infection

98.11

DMSO : 2 mg/mL (ultrasonic)

O=C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

C65H102N16O15

1347.60

[1]Gedvilaite A, et al. Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes. Viruses. 2015 Jul 29;7 (8) :4204-29.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P11303/PADRE-peptide-SDS-MedChemExpress.pdf

Peptides

No Development Reported