Palmitoylglycine (standaard)

Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].

2441-41-0

N-palmitoyl glycine (Standard)

12352211

Calcium Channel; NO Synthase; Reference Standards

Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Inflammation/Immunology; Neurological Disease

O=C(O)CNC(CCCCCCCCCCCCCCC)=O

C18H35NO3

313.48

[1]Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74 (1) :213-24.|[2]Xu H, et al. N-Palmitoyl glycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome[J]. medRxiv, 2024: 2024.10. 21.24315897.|[3]Bradshaw HB, et al. Novel endogenous N-acyl glycines identification and characterization. Vitam Horm. 2009;81:191-205.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W074890R/

Reference Standards