Palmitoyltetrapeptide-10

Palmitoyl tetrapeptide-10 is a bioactive peptide. Palmitoyl tetrapeptide-10 works synergistically with other active ingredients to increase the expression of corneodesmosin (a marker of keratinocyte adhesion) and filaggrin (a marker of keratinocyte terminal differentiation), thereby reducing skin permeability and improving skin barrier function. Palmitoyl tetrapeptide-10 can be used in the research of sensitive skin syndrome and skin pigmentation[1][2].

887140-79-6

12352209

Others

Others

Metabolism-protein/nucleotide metabolism

Endocrinology; Metabolic Disease

99.46

10 mM in DMSO

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](CCCCN)NC(CCCCCCCCCCCCCCC)=O

C41H72N6O7

761.05

[1]Wenner K, et al. An Open-Label Study Assessing the Efficacy and Tolerability of a Skincare Regimen in Subjects of Different Ethnicities with Moderate-to-Severe Hyperpigmentation. J Cosmet Dermatol. 2022;21 (6) :2497-2507.|[2]Polena H, et al. Evaluation of the sensitive skin syndrome and the effect of a dermo-cosmetic treatment in Thai and Polish subjects. Int J Cosmet Sci. 2025 Aug 19.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P5269/Palmitoyl-tetrapeptide-10-SDS-MedChemExpress.pdf

Peptides

No Development Reported