Pancreatrisch polypeptide (PPY) (NM 002722) Humaan Recombinant eiwit

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Purified recombinant protein of Human pancreatic polypeptide (PPY), Ala30-Arg88, N-terminal His-PDCD1 (Pro21-Val170) tag, expressed in E. coli, 50ug

PNP; PP

5539

P01298

NM_002722

17q21.31

E. coli

N-terminal His-PDCD1 (Pro21-Val170) tag

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0

Secreted Protein

23.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

PPY

Human

NP_002713

https://www.ncbi.nlm.nih.gov/gene/5539

https://www.uniprot.org/uniprot/P01298

https://www.ncbi.nlm.nih.gov/nuccore/NM_002722

https://www.ncbi.nlm.nih.gov/nuccore/NP_002713