PANK2 Antilichaam - middengebied: Biotine (ARP60834 P050-Biotine)

Pantothenate kinase 3

HSS, HARP, PKAN, NBIA1, C20orf48

80025

Q9BZ23-4

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of HUMAN PANK2

This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.

UBC; DHX36; QRICH2; LXN; YWHAQ; VDAC1; RASGRF2

Biotin

Polyclonal Antibody

WB

Affinity Purified

PANK2 is supported by BioGPS gene expression data to be expressed in COLO205

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 92%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Wet Ice

460

PANK2

PANK2

Rabbit

Pantothenate kinase 2, mitochondrial

FGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCAL