PANK2 Mouse Monoclonal Antibody [Kloon ID: LBI3H9]

This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) PANK2 mouse monoclonal antibody, clone LBI3H9

C20orf48; HARP; HSS; NBIA1; PKAN

Homo sapiens pantothenate kinase 2 (PANK2), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

80025

Q9BZ23

Unconjugated

Metabolic pathways, Pantothenate and CoA biosynthesis

Metabolic pathways, Pantothenate and CoA biosynthesis

WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PANK2

https://www.ncbi.nlm.nih.gov/gene/?term=80025

https://www.uniprot.org/uniprot/Q9BZ23