PAPOL A+B+G Polyklonale Antilichaam, Cy3 Vervoeging

Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly (A) site that leads to synthesis of the poly (A) tail at the 3-prime end of the upstream cleavage product. The poly (A) polymerase (PAP) is required The adenosine addition reaction depends on poly (A) polymerase (PAP) activity. The testis express PAP-beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-beta plays a critical role in male germ cell production. PAP-beta-deficient transgenic mice display impaired expression of haploid-specific genes that are necessary for spermatogenesis. The intronless gene encoding human PAP-beta maps to chromosome 7p22.3.

PAPOL A/B/G; PAP alpha/beta/gamma; PapIII; MGC5378; PAP alpha; PAP beta; PAP gamma; PAP; PAP-alpha; PAP-beta; PAP-gamma; PAPOLA; PAPOLB; PAPOLG; PAPOA_HUMAN; PAPOB_HUMAN; PAPOG_HUMAN; Plap; polyA polymerase alpha; Polynucleotide adenylyltransferase alpha; polyA polymerase beta testis specic; polyA polymerase beta; polynucleotide adenylyltransferase beta; TPAP; Testis-specic polyA polymerase.

10914, 56903, 64895

P51003, Q9NRJ5, Q9BWT3

Cytoplasm, Nucleus, Lumenal

Human, Mouse, Rat

81-190/745

PAPOL A+B+G

Cy3

KLH conjugated synthetic peptide derived from human PAPOLA/PAPOLB/PAPOLG

WB, IF (IHC-P)

Purified by Protein A.

512,550nm/570,615nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

10914, 56903, 64895