PARP16 Polyklonale Antilichaam, Cy3 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Poly (ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly (ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly (ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.
C15orf30; Chromosome 15 open reading frame 30; EC 2.4.2.30; FLJ25281; PAR16_HUMAN; PARP 16; PARP-16; Parp16; Poly ADP ribose polymerase family member 16; Poly [ADP ribose] polymerase 16; Poly [ADP-ribose] polymerase 16.
54956
Q8N5Y8
• Rabbit
Human
101-200/322
PARP16
• Polyclonal
• IgG
Cy3
KLH conjugated synthetic peptide derived from human PARP16
WB, IF (IHC-P)
Purified by Protein A.
512,550nm/570,615nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
54956
Mouse, Rat, Dog, Cow, Sheep, Horse, Rabbit
Beschrijving
PARP16 Polyklonale Antilichaam, Cy3 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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