PARP2 Antilichaam - middengebied: FITC (ARP33758_P050-FITC)

Poly (ADP-ribose) polymerase 2

ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2

10038

Q9UGN5

NP_005475

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human PARP2

This gene encodes poly (ADP-ribosyl) transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

UHRF1; Npm1; TFAP4; UBC; RNF146; H3F3A; CBX5; TRIM28; CHD1L; TNP2; HSPA2; BUB3; CASP8; XRCC1; PARP1; CENPB; CENPA

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IF, WB

Affinity Purified

PARP2 is strongly supported by BioGPS gene expression data to be expressed in Raji

0.5 mg/ml

Cow: 86%; Dog: 86%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

61kDa

Malanga, M. et al., (2004) J. Biol. Chem. 279 (7), 5244-5248

Wet Ice

534

PARP2

PARP2

Rabbit

Poly [ADP-ribose] polymerase 2

NM_005484

LLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAHPEA