PARP3 Antilichaam - C-terminaal gebied: Biotine (ARP33760_P050-Biotine)

Poly (ADP-ribose) polymerase family member 3

IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3

10039

Q9Y6F1

NP_005476

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly (ADP-ribosyl) transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

UBC; APP; PARP3; HIST1H1A; PARP1; HIST2H3C; MTHFD2; HIST2H2BE; RPA3

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 92%; Dog: 91%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 85%; Rabbit: 100%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

59kDa

Augustin, A., et al., (2003) J. Cell. Sci. 116 (Pt 8), 1551-1562

Wet Ice

532

PARP3

PARP3

Rabbit

Poly [ADP-ribose] polymerase 3

NM_005485

LGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVP