Paxilline (fosfo-Tyr118) Antilichaam

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) .

5829

P49023

NP_001074324.1

Human, Mouse, Rat

Paxillin (Phospho-Tyr118) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 118 (H-V-Y (p) -S-F) derived from Human Paxillin.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

68 kDa

This antibody detects endogenous level of Paxillin only when phosphorylated at tyrosine 118.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

PXN

Paxillin

Homo sapiens

Tao WA, et al. (2005) Nat Methods. 2 (8) : 591-598. Zhang Y, et al. (2005) Mol Cell Proteomics. 4 (9) : 1240-1250. Sanders MA, et al. (2005) J Biol Chem. 280 (25) : 23516-23522. Rush J, et al. (2004) Nat Biotechnol. 23 (1) : 94-101.

IKBA, MAD3, NFKBI, PAXI, PXN

WB, IHC

170932514

Liquid